This article has been cited by other articles in PMC. Methods Dietary patterns were extrapolated for participants from the Women's Health Aging Project.
Four dietary patterns were identified: high fat, Mediterranean, junk food, and low fat. Discussion This study highlights the potential of diet to influence neurodegenerative disease and as a potential modifiable lifestyle risk factor for Alzheimer's disease.
Introduction Diet may play a substantial role in the Alzheimer's disease AD symptomatology and offer great potential for nonpharmacological prevention. Epidemiological evidence has suggested increased adherence to a Mediterranean diet low glycemic index and higher consumption of omega-3 polyunsaturated fatty acids  were associated with a decrease in AD biomarker burden.
Furthermore, male and mixed cohort studies predominate the research, and to date, no study has investigated this relationship specifically in women.
Impacts of higher male mortality, vascular risk factors, and the postmenopausal loss of estrogenic neuroprotection suggest females are 1. Given sex differences in AD risk, research is needed for those at greater risk of disease. Methods 2.
Study population Participants were sought from the follow-up of the Women's Health Ageing Project WHAPan epidemiologically sourced prospective study of healthy aging Australian women. Briefly, women within the Melbourne metropolitan area were identified by random digit dialing in Inparticipants were re-contacted and invited to participate in a late-life health study.
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Clinical assessments were conducted on participants by trained field researchers. The clinical assessments included a battery of validated measures of physical health, sociodemographics, lifestyle, cognitive function, psychological health, and biomarkers.
A complete methodology has been published elsewhere . The DQES v2 incorporates 80 food items with frequency response options on 74 of these items.
Dietary patterns were extrapolated from food groupings using iterated principal factor analysis with oblique varimax rotation due to the presumed intercollinearity and nonindependence of dietary patterns.